Tuberculosis (TB) is an infectious disease placed among the 10 main causes of death worldwide. It is estimated that around 30% of the world’s population has been infected with its latent form. Most TB cases affect the lungs. The Dynamic hypothesis states that TB lesions spread inside the lungs mainly through the bronchial tree. Following the 3R’s principles, mathematical models are a powerful tool to simulate pulmonary infections. Virtual bronchial tree computed until now did not include the lobe and segments structure of lungs. These characteristics are important for the encapsulation of TB lesions. In this project it is built a 3D virtual lung that resembles the lobes and segments structure of a macaque lung 2021/2022